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当前位置：医疗器械网> 资讯中心>使用变色水凝胶制作微流体压力传感器，实现非接触式压力测量，精度至10mbar，24年3月《Scientific Reports》

使用变色水凝胶制作微流体压力传感器，实现非接触式压力测量，精度至10mbar，24年3月《Scientific Reports》

来源：微纳立方科技(北京)有限公司分类：会展 2024-04-28 10:00:07 23阅读次数

这是微纳立方第50篇微流控推文。

Lucie Ducloué等人实现了使用变色水凝胶制作微流体压力传感器，实现非接触式压力测量，压力测量精度可达20毫巴，分辨率约为10毫巴。这篇研究于24年3月15日以“Color-switching hydrogels as integrated microfluidic pressure sensors”为名发表于《Scientific Reports》（Nature Research）.

微流体压力测量对于流动控制、流体特性表征和监控至关重要，但面临诸如分辨率、非侵入性或易用性等具体挑战。作者团队展示了一种全集成的多路复用（在多个位置或多个通道上进行压力测量）光流体压力传感器，该传感器与流动路径完全解耦（传感器与微流体互不影响），能够在任何微流控通道沿线进行局部压力测量，并且不影响流体流动。

传感器依赖于一种软机械激活的水凝胶，在压力变化时改变颜色。水凝胶通过一层薄膜与通道中循环的流体隔离，允许使用不同类型的流体。实验中用彩色摄像头通过透明PDMS成像水凝胶，实现流体压力的直接、简易、无接触式测定，压力测量精度可达20毫巴，分辨率约为10毫巴。

此外，通过调整传感单元的机械属性，可以调整灵敏度和可接受的压力范围。利用此光子水凝胶快速响应时间和细致的空间分辨率，还可以用来获取二维压力或变形图。

[1]. Ducloué L, Haque M A, Goral M, et al. Color-switching hydrogels as integrated microfluidic pressure sensors[J]. Scientific Reports, 2024, 14(1): 6333.

论文地址（或点击文末阅读原文查看）：https://www.nature.com/articles/s41598-024-56140-z

用到的产品：Fluigent LineUp系列Flow EZ压力泵。

使用Flow EZ施加压力以校准传感器，范围从0毫巴到140毫巴。

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[2]Declaration of app\common\model\News::getAllList($filter = Array, $limit = 16, $order = Array, $with = Array) should be compatible with app\common\model\BaseModel::getAllList($filter = Array, $with = Array, $limit = 0, $sort = Array, $field = 'a.*', $join = Array)
[2]Declaration of app\common\model\Company::getAllList($filter = Array, $limit = 20) should be compatible with app\common\model\BaseModel::getAllList($filter = Array, $with = Array, $limit = 0, $sort = Array, $field = 'a.*', $join = Array)
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[8]Only variables should be passed by reference
[2]Declaration of app\common\model\NewsComment::getAllList($filter = Array, $limit = 16) should be compatible with app\common\model\BaseModel::getAllList($filter = Array, $with = Array, $limit = 0, $sort = Array, $field = 'a.*', $join = Array)
[8192]Function create_function() is deprecated
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[2]Declaration of app\common\model\Topic::getList($filter = Array) should be compatible with app\common\model\BaseModel::getList($filter = Array, $sort = Array)
[2]Declaration of app\common\model\Topic::getAllList($filter = Array, $field = 'id,md5,tit...', $limit = 0) should be compatible with app\common\model\BaseModel::getAllList($filter = Array, $with = Array, $limit = 0, $sort = Array, $field = 'a.*', $join = Array)
[2]Declaration of app\common\model\TopicInfoList::getAllList($filter = Array, $limit = 8) should be compatible with app\common\model\BaseModel::getAllList($filter = Array, $with = Array, $limit = 0, $sort = Array, $field = 'a.*', $join = Array)
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[ SQL ] SHOW COLUMNS FROM `user` [ RunTime:0.000815s ]
[ SQL ] SELECT `a`.* FROM `user` `a` INNER JOIN `news` `b` ON `a`.`id`=`b`.`user_id` GROUP BY `a`.`id` ORDER BY `b`.`id` DESC LIMIT 10 [ RunTime:0.009895s ]
[ SQL ] SELECT * FROM `user_info` WHERE `user_id` IN (351,466,458,209,372,521,819,385,657,412) [ RunTime:0.000719s ]
[ SQL ] SHOW COLUMNS FROM `seo` [ RunTime:0.000897s ]
[ SQL ] SELECT * FROM `seo` WHERE `column_type` = '02' AND `page_type` = 'news' AND `info_id` = 7507 LIMIT 1 [ RunTime:0.000179s ]
[ SQL ] SELECT * FROM `news_belong_category` WHERE `news_id` = 7507 [ RunTime:0.002033s ]
[ SQL ] SELECT * FROM `news_belong_category` WHERE `news_id` = 4314 [ RunTime:0.001839s ]
[ SQL ] SELECT * FROM `news_belong_category` WHERE `news_id` = 2105 [ RunTime:0.001885s ]
[ SQL ] SELECT * FROM `news_belong_category` WHERE `news_id` = 1774 [ RunTime:0.001697s ]
[ SQL ] SELECT * FROM `news_belong_category` WHERE `news_id` = 3877 [ RunTime:0.001813s ]
[ SQL ] SELECT * FROM `news_belong_category` WHERE `news_id` = 5800 [ RunTime:0.001765s ]
[ SQL ] SELECT * FROM `news_belong_category` WHERE `news_id` = 4507 [ RunTime:0.001711s ]
[ SQL ] SELECT * FROM `news_belong_category` WHERE `news_id` = 3101 [ RunTime:0.001641s ]
[ SQL ] SELECT * FROM `news_belong_category` WHERE `news_id` = 2399 [ RunTime:0.001630s ]
[ SQL ] SELECT * FROM `news_belong_category` WHERE `news_id` = 2271 [ RunTime:0.001898s ]
[ SQL ] SELECT * FROM `user` WHERE `id` = 761 LIMIT 1 [ RunTime:0.000285s ]
[ SQL ] SELECT COUNT(*) AS tp_count FROM `user_follow` WHERE `follow_user_id` = 351 LIMIT 1 [ RunTime:0.000270s ]
[ SQL ] SELECT COUNT(*) AS tp_count FROM `user_follow` WHERE `user_id` = 351 LIMIT 1 [ RunTime:0.000201s ]
[ SQL ] SELECT COUNT(*) AS tp_count FROM `user_follow` WHERE `follow_user_id` = 466 LIMIT 1 [ RunTime:0.000257s ]
[ SQL ] SELECT COUNT(*) AS tp_count FROM `user_follow` WHERE `user_id` = 466 LIMIT 1 [ RunTime:0.000197s ]
[ SQL ] SELECT COUNT(*) AS tp_count FROM `user_follow` WHERE `follow_user_id` = 458 LIMIT 1 [ RunTime:0.000211s ]
[ SQL ] SELECT COUNT(*) AS tp_count FROM `user_follow` WHERE `user_id` = 458 LIMIT 1 [ RunTime:0.000177s ]
[ SQL ] SELECT COUNT(*) AS tp_count FROM `user_follow` WHERE `follow_user_id` = 209 LIMIT 1 [ RunTime:0.000164s ]
[ SQL ] SELECT COUNT(*) AS tp_count FROM `user_follow` WHERE `user_id` = 209 LIMIT 1 [ RunTime:0.000169s ]
[ SQL ] SELECT COUNT(*) AS tp_count FROM `user_follow` WHERE `follow_user_id` = 372 LIMIT 1 [ RunTime:0.000156s ]
[ SQL ] SELECT COUNT(*) AS tp_count FROM `user_follow` WHERE `user_id` = 372 LIMIT 1 [ RunTime:0.000168s ]
[ SQL ] SELECT COUNT(*) AS tp_count FROM `user_follow` WHERE `follow_user_id` = 521 LIMIT 1 [ RunTime:0.000206s ]
[ SQL ] SELECT COUNT(*) AS tp_count FROM `user_follow` WHERE `user_id` = 521 LIMIT 1 [ RunTime:0.000132s ]
[ SQL ] SELECT COUNT(*) AS tp_count FROM `user_follow` WHERE `follow_user_id` = 819 LIMIT 1 [ RunTime:0.000120s ]
[ SQL ] SELECT COUNT(*) AS tp_count FROM `user_follow` WHERE `user_id` = 819 LIMIT 1 [ RunTime:0.000140s ]
[ SQL ] SELECT COUNT(*) AS tp_count FROM `user_follow` WHERE `follow_user_id` = 385 LIMIT 1 [ RunTime:0.000148s ]
[ SQL ] SELECT COUNT(*) AS tp_count FROM `user_follow` WHERE `user_id` = 385 LIMIT 1 [ RunTime:0.000192s ]
[ SQL ] SELECT COUNT(*) AS tp_count FROM `user_follow` WHERE `follow_user_id` = 657 LIMIT 1 [ RunTime:0.000136s ]
[ SQL ] SELECT COUNT(*) AS tp_count FROM `user_follow` WHERE `user_id` = 657 LIMIT 1 [ RunTime:0.000137s ]
[ SQL ] SELECT COUNT(*) AS tp_count FROM `user_follow` WHERE `follow_user_id` = 412 LIMIT 1 [ RunTime:0.000153s ]
[ SQL ] SELECT COUNT(*) AS tp_count FROM `user_follow` WHERE `user_id` = 412 LIMIT 1 [ RunTime:0.000145s ]

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